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Low Threshold Calcium Currents in TC cells (Destexhe et al 1998)
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Accession:
279
In Destexhe, Neubig, Ulrich, and Huguenard (1998) experiments and models examine low threshold calcium current's (IT, or T-current) distribution in thalamocortical (TC) cells. Multicompartmental modeling supports the hypothesis that IT currents have a density at least several fold higher in the dendrites than the soma. The IT current contributes significantly to rebound bursts and is thought to have important network behavior consequences. See the paper for details. See also http://cns.iaf.cnrs-gif.fr Correspondance may be addressed to Alain Destexhe: Destexhe@iaf.cnrs-gif.fr
Reference:
1 .
Destexhe A, Neubig M, Ulrich D, Huguenard J (1998) Dendritic low-threshold calcium currents in thalamic relay cells.
J Neurosci
18
:3574-88
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Thalamus geniculate nucleus/lateral principal GLU cell;
Channel(s):
I Na,t;
I T low threshold;
I K;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Dendritic Action Potentials;
Bursting;
Ion Channel Kinetics;
Parameter Fitting;
Simplified Models;
Influence of Dendritic Geometry;
Detailed Neuronal Models;
Calcium dynamics;
Rebound firing;
Implementer(s):
Destexhe, Alain [Destexhe at iaf.cnrs-gif.fr];
Search NeuronDB
for information about:
Thalamus geniculate nucleus/lateral principal GLU cell
;
I Na,t
;
I T low threshold
;
I K
;
Download the displayed file
/
dendtc
cells
README
cadecay.mod
*
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Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008)
Pyramidal Neuron: Deep, Thalamic Relay and Reticular, Interneuron (Destexhe et al 1998, 2001)
Rat LGN Thalamocortical Neuron (Connelly et al 2015, 2016)
hh2.mod
*
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Inferring connection proximity in electrically coupled networks (Cali et al. 2007)
Pyramidal Neuron: Deep, Thalamic Relay and Reticular, Interneuron (Destexhe et al 1998, 2001)
T channel currents (Vitko et al 2005)
T channel currents (Vitko et al 2005)
T channel currents (Vitko et al 2005)
Thalamic reticular neurons: the role of Ca currents (Destexhe et al 1996)
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
ITGHK.mod
*
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Rat LGN Thalamocortical Neuron (Connelly et al 2015, 2016)
VClamp.mod
*
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CA1 pyramidal neuron: as a 2-layer NN and subthreshold synaptic summation (Poirazi et al 2003)
T channel currents (Vitko et al 2005)
T channel currents (Vitko et al 2005)
T channel currents (Vitko et al 2005)
Thalamic reticular neurons: the role of Ca currents (Destexhe et al 1996)
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
El.oc
*
Other models using El.oc:
T channel currents (Vitko et al 2005)
T channel currents (Vitko et al 2005)
T channel currents (Vitko et al 2005)
Thalamic reticular neurons: the role of Ca currents (Destexhe et al 1996)
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
loc200.oc
loc3.oc
*
Other models using loc3.oc:
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
Thalamocortical Relay cell under current clamp in high-conductance state (Zeldenrust et al 2018)
locD.oc
mosinit.hoc
*
Other models using mosinit.hoc:
T channel currents (Vitko et al 2005)
T channel currents (Vitko et al 2005)
T channel currents (Vitko et al 2005)
Thalamic reticular neurons: the role of Ca currents (Destexhe et al 1996)
rundemo.hoc
tc1_cc.oc
tc200_cc.oc
tc200_vc.oc
tc3_cc.oc
tcD_vc.oc
load_file("nrngui.hoc") xopen("rundemo.hoc")
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