Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
ModelDB is moving. Check out our new site at
The corresponding page is
Caffeine-induced electrical oscillations in Aplysia neurons (Komendantov, Kononenko 2000)
Download zip file
Help downloading and running models
It has been found that in cultured Aplysia neurons bath applications of 40 mM cafffeine evokes oscillations of the membrane potential with about a 40 mV amplitude with a frequency of 0.2 to 0.5 Hz. The most probable mechanism of these caffeine-induced oscillations is inhibition of voltage-activated outward potassium current and, as can be seen from our mathematical modeling, slowdown of inactivation of inward sodium current. It seems likely that these oscillations have a purely membrane origin. Please see paper for results and details.
Komendantov AO, Kononenko NI (2000) Caffeine-induced oscillations of the membrane potential in Aplysia Neurons.
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Aplysia cultured neuron;
Komendantov, Alexander O [akomenda at tulane.edu];
Kononenko, Nikolai I [nik137 at lamar.colostate.edu];
for information about:
File not selected
<- Select file from this column.
Loading data, please wait...