The Minimal Cell Model (MCM) :
Av-Ron, E, Parnas, H, Segel, LA (1991) A minimal biophysical model for
an excitable and oscillatory neuron.
Biol. Cybern. 65:487-500
implemented in SNNAP (http://snnap.uth.tmc.edu).
The minimal cell model (MCM) is a reduced Hodgkin-Huxley model that can
exhibit excitable and oscillatory behavior. It consists of two
ordinary differential equations, dV/dt for membrane voltage and dW/dt
for potassium activation and sodium inactivation. The MCM has a stable
membrane potential of -60mV. With constant input current of 10uA/cm2, it
exhibits oscillations of 150Hz. It is based on the work by FitzHugh and
Rinzel.
Provided by Evyatar Av-Ron <eav-ron@uth.tmc.edu>
To run:
Download and unzip the zip file into a directory that has no spaces in its path.
Double click on the SNNAP8.jar file (where the 8 might be a different version)
Click on start simulation, then File--> Load simulation and browse to the MCM folder and
select the MCM.smu file.
Finally click on start.
|