Multiple modes of a conditional neural oscillator (Epstein, Marder 1990)

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Accession:42321
We present a model for a conditional bursting neuron consisting of five conductances: Hodgkin-Huxley type time- and voltage-dependent Na+ and K+ conductances, a calcium activated voltage-dependent K+ conductance, a calcium-inhibited time- and voltage-dependent Ca++ conductance, and a leakage Cl- conductance. Different bursting and silent modes and transitions between them are analyzed in the model and compared to bursting modes in experiment. See the paper for details.
Reference:
1 . Epstein IR, Marder E (1990) Multiple modes of a conditional neural oscillator. Biol Cybern 63:25-34 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s): I Chloride; I Na,t; I K; I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: SNNAP;
Model Concept(s): Bursting; Invertebrate;
Implementer(s): Baxter, Douglas;
Search NeuronDB for information about:  I Chloride; I Na,t; I K; I Sodium; I Calcium; I Potassium;
>------------------------------->--------------------------------------->
  VAR_TO_GRAPH: 		>	List of current contributing	>
				>		to ion pools		>
>------------------------------->--------------------------------------->
	GRPH_CHNL:		>	Graph channel			>
>------------------------------->--------------------------------------->
	1			>	GAIN of Channel			>
	time<{ivr}            	>	Var Name for X-axis		>
		4           	>	Number of Tic Marks		>
		0.00        	>	Min Value of X			>
		4000.00     	>	Max Value of X			>
		yellow       	>	Color of Range			>
	V[a....]<{ivr}        	>	Var Name for Y-axis		>
		7           	>	Number of Tic Marks		>
		-80.00      	>	Min Value of Y			>
		60.00       	>	Max Value of Y			>
		red           	>	Color of RAnge			>
	Cion[Ca.a...]<{ivr}   	>	Var Name for Y-axis		>
		5           	>	Number of Tic Marks		>
		0.00        	>	Min Value of Y			>
		1.00        	>	Max Value of Y			>
		green         	>	Color of RAnge			>
>------------------------------->--------------------------------------->
	GRPH_CHNL:		>	Graph channel			>
>------------------------------->--------------------------------------->
	1			>	GAIN of Channel			>
	Cion[Ca.a...]<{ivr}   	>	Var Name for X-axis		>
		1           	>	Number of Tic Marks		>
		0.00        	>	Min Value of X			>
		0.5        	>	Max Value of X			>
		green        	>	Color of Range			>
	Gvd[Ca.a...]<{ivr}	>	Var Name for Y-axis		>
		1           	>	Number of Tic Marks		>
		0.00      	>	Min Value of Y			>
		0.06        	>	Max Value of Y			>
		gold          	>	Color of RAnge			>
>------------------------------->--------------------------------------->
	END:			>					>
>------------------------------->--------------------------------------->

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