Pyramidal neurons: IKHT offsets activation of IKLT to increase gain (Fernandez et al 2005)

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Accession:48506
This matlab model was supplied by Dr Fernandez. It provides the model specification for the below paper. The influence of a high threshold K current on low threshold K and Na currents (especially frequency-current relationships) are studied in the paper with both experiments and modeling. Please see the reference for more and details.
Reference:
1 . Fernandez FR, Mehaffey WH, Molineux ML, Turner RW (2005) High-threshold K+ current increases gain by offsetting a frequency-dependent increase in low-threshold K+ current. J Neurosci 25:363-71 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type:
Brain Region(s)/Organism:
Cell Type(s): ELL pyramidal cell;
Channel(s): I Na,t; I K; I Potassium; I_KHT; I_KLT;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s): Activity Patterns; Ion Channel Kinetics;
Implementer(s): Fernandez FR [ffernand at ucalgary.ca]; Mehaffey WH ;
Search NeuronDB for information about:  I Na,t; I K; I Potassium; I_KHT; I_KLT;
 
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IKHToffsetsIKLT
                            
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