Breakdown of accmmodation in nerve: a possible role for INAp (Hennings et al 2005)

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Accession:55749
The present modeling study suggests that persistent, low-threshold, rapidly activating sodium currents have a key role in breakdown of accommodation, and that breakdown of accommodation can be used as a tool for studying persistent sodium current under normal and pathological conditions. See paper for more and details.
Reference:
1 . Hennings K, Arendt-Nielsen L, Andersen OK (2005) Breakdown of accommodation in nerve: a possible role for persistent sodium current. Theor Biol Med Model 2:16 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Spinal cord lumbar motor neuron alpha ACh cell; Myelinated neuron;
Channel(s): I Na,p; I Na,t; I K;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s): Action Potential Initiation; Action Potentials; Pathophysiology; Electrotonus;
Implementer(s): Hennings, Kristian [krist at hst.auc.dk];
Search NeuronDB for information about:  Spinal cord lumbar motor neuron alpha ACh cell; I Na,p; I Na,t; I K; 
#include "mex.h"
#include "mxUtility.h"

int isScalar(const mxArray *prhs) {
	if(!mxIsDouble(prhs) || mxIsComplex(prhs) || 
		!(mxGetM(prhs) == 1 && mxGetN(prhs) == 1)) {
		return 0;
	}
	return 1;
}

long isVector(const mxArray *prhs) {
	if(mxIsDouble(prhs) && !mxIsComplex(prhs) && 
		(mxGetM(prhs) == 1 || mxGetN(prhs) == 1)) {
		return mxGetM(prhs) == 1 ? mxGetN(prhs) : mxGetM(prhs);
	}
	return 0;
}

long idx(long i,long j,long M) {
  return i + j*M;
}

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