CA1 pyramidal neuron synaptic integration (Li and Ascoli 2006, 2008)

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Accession:71312
The model shows how different input patterns (irregular & asynchronous, irregular & synchronous, regular & asynchronous, regular & synchronous) affect the neuron's output rate when 1000 synapses are distributed in the proximal apical dendritic tree of a hippocampus CA1 pyramidal neuron.
References:
1 . Li X, Ascoli GA (2006) Computational simulation of the input-output relationship in hippocampal pyramidal cells. J Comput Neurosci 21:191-209 [PubMed]
2 . Li X, Ascoli GA (2008) Effects of synaptic synchrony on the neuronal input-output relationship. Neural Comput 20:1717-31 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Hippocampus CA1 pyramidal GLU cell;
Channel(s): I Na,t; I A; I K; I h;
Gap Junctions:
Receptor(s): AMPA; NMDA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Detailed Neuronal Models; Synaptic Integration;
Implementer(s): Li, Xiaoshen [xsli2 at yahoo.com];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal GLU cell; AMPA; NMDA; I Na,t; I A; I K; I h;
 
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