ModelDB: CA1 pyramidal neuron: conditional boosting of dendritic APs (Watanabe et al 2002)

ModelDB is moving. Check out our new site at https://modeldb.science. The corresponding page is https://modeldb.science/7386.

CA1 pyramidal neuron: conditional boosting of dendritic APs (Watanabe et al 2002)

Download zip file
Help downloading and running models

Model Information
Model File
Citations
Model Views
Simulation Platform

Accession:7386

Model files from the paper Watanabe S, Hoffman DA, Migliore M, Johnston D (2002). The experimental and modeling results support the hypothesis that dendritic K-A channels and the boosting of back-propagating action potentials contribute to the induction of LTP in CA1 neurons. See the paper for details. Questions about the model may be addressed to Michele Migliore: michele.migliore@pa.ibf.cnr.it
Reference:
1 . Watanabe S, Hoffman DA, Migliore M, Johnston D (2002) Dendritic K+ channels contribute to spike-timing dependent long-term potentiation in hippocampal pyramidal neurons. Proc Natl Acad Sci U S A 99:8366-71 [PubMed]

Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):	Hippocampus CA1 pyramidal GLU cell;
Channel(s):	I Na,t; I A; I K;
Gap Junctions:
Receptor(s):	AMPA;
Gene(s):
Transmitter(s):
Simulation Environment:	NEURON;
Model Concept(s):	Dendritic Action Potentials; Coincidence Detection; Active Dendrites; Detailed Neuronal Models; Action Potentials;
Implementer(s):	Migliore, Michele [Michele.Migliore at Yale.edu];

Search NeuronDB for information about: Hippocampus CA1 pyramidal GLU cell; AMPA; I Na,t; I A; I K;

File not selected

<- Select file from this column.

Load Model View

Loading data, please wait...