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Feedforward heteroassociative network with HH dynamics (Lytton 1998)

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Accession:7399
Using the original McCulloch-Pitts notion of simple on and off spike coding in lieu of rate coding, an Anderson-Kohonen artificial neural network (ANN) associative memory model was ported to a neuronal network with Hodgkin-Huxley dynamics.
Reference:
1 . Lytton WW (1998) Adapting a feedforward heteroassociative network to Hodgkin-Huxley dynamics. J Comput Neurosci 5:353-64 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s):
Channel(s): I Na,t; I K;
Gap Junctions:
Receptor(s): GabaA; AMPA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Pattern Recognition; Temporal Pattern Generation; Spatio-temporal Activity Patterns; Simplified Models; Attractor Neural Network;
Implementer(s): Lytton, William [bill.lytton at downstate.edu];
Search NeuronDB for information about:  GabaA; AMPA; I Na,t; I K;
/
lytton98
README
AMPA.mod
GABAA.mod
kdr.mod
matrix.mod *
misc.mod.orig
naf.mod *
passiv.mod *
precall.mod
pregen.mod *
pregencv.mod
pulsecv.mod
sinstim.mod *
vecst.mod
bg.inc *
boxes.hoc *
declist.hoc *
decvec.hoc *
default.hoc *
directory
fig5.gif
grvec.hoc
init.hoc
labels.hoc
loadr.hoc *
local.hoc *
mosinit.hoc *
net.hoc
nrnoc.hoc *
params.hoc
presyn.inc
proc.hoc
run.hoc
simctrl.hoc *
sns.inc *
snsarr.inc
snscode.hoc
snshead.inc *
spkts.hoc
tmpl.hoc
xtmp
                            
NEURON {  POINT_PROCESS GABAA }
:   GABA SYNAPSE (GABA-A receptors)
:
:   Parameters estimated from whole cell recordings of GABA-A synaptic currents 
:   from dentate granule cells: Otis TS and Mody I (1992) Modulation of decay 
:   kinetics and frequency of GABA_A receptor-mediated spontaneous inhibitory
:   postsynaptic currents in hippocampal neurons.  Neurosci. 49: 13-32.
:
:   GABALOW was created to allow the use two types of GABA-A currents in the
:   same simulation.
PARAMETER {
  Cdur	= 1.0	(ms)		: transmitter duration (rising phase)
  Alpha	= 0.53	(/ms mM)	: forward (binding) rate
  Beta	= 0.18	(/ms)		: backward (unbinding) rate
  Erev	= -75	(mV)		: reversal potential
  Deadtime = 1.	(ms)		: mimimum time between release events
  GMAX = 1	(uS)		: maximum conductance
  DELAY = 2
}
INCLUDE "sns.inc"
:** AMPA

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