Synaptic integration of an identified nonspiking interneuron in crayfish (Takashima et al 2006)

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This GENESIS simulation shows how a single or compound excitatory synaptic potential evoked by mechanosensory stimulation spreads over the dendrites of the LDS interneuron that is one of the identified nonspiking interneurons in the central nervous system of crayfish Procambarus clarkii. The model is based on physiological experiments carried out by Akira Takashima using single-electrode voltage clamp techniques and also 3-D morphometry of the interneuron carried out by Ryou Hikosaka using confocal laser scanning microscopic techniques. The physiological and morphological studies were coordinated by Masakazu Takahata.
1 . Takashima A, Hikosaka R, Takahata M (2006) Functional significance of passive and active dendritic properties in the synaptic integration by an identified nonspiking interneuron of crayfish. J Neurophysiol 96:3157-69 [PubMed]
2 . Takahata M, Takashima A, Hikosaka R (2000) Information processing by nonspiking interneurons: passive and active properties of dendritic membrane determine synaptic integration. Biosystems 58:143-9 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism:
Cell Type(s): Crayfish identified nonspiking interneuron;
Channel(s): I A; I K; I Potassium;
Gap Junctions:
Simulation Environment: GENESIS;
Model Concept(s): Influence of Dendritic Geometry; Invertebrate; Synaptic Integration;
Implementer(s): Takahata, Masakazu [takahata at];
Search NeuronDB for information about:  I A; I K; I Potassium;
// genesis - xtools.g - Functions used in the control panel
// This file was developed by
//       Akira Takashima.
//       Department of Biological Sciences
//       Faculry of Science
//       Hokkaido University
//       Sapporo Japan
//       Last update on 22 Jan. 2007

// advances the simulation by the amount of time given in the dialog

function stepbutton(widget)
    str widget
    echo step  {getfield {widget} value} msec.
    step {getfield {widget} value} -time

function clockbutton(widget)
    str widget
    echo "dt = " {getfield {widget} value} msec.
    setclock 0 {getfield {widget} value} 

// make hsolve /cell/solve

function delete_hsolve
    pushe /
    delete /cell/solve
    echo "/cell/solve are deleted!"

// choose integration method 

/*function integ_method(widget)
    str widget
    echo "Integration Method is " {getfield {widget} value}.
    setmethod {getfield {widget} value} 


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