Lamprey spinal CPG neuron (Huss et al. 2007)

 Download zip file 
Help downloading and running models
This is a model of a generic locomotor network neuron in the lamprey spinal cord. The given version is assumed to correspond to an interneuron; motoneurons can also be modelled by changing the dendritic tree morphology.
1 . Huss M, Lansner A, Wallén P, El Manira A, Grillner S, Kotaleski JH (2007) Roles of ionic currents in lamprey CpG neurons: a modeling study. J Neurophysiol 97:2696-711 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s): I Na,t; I A; I K; I K,Ca; I_Ks;
Gap Junctions:
Simulation Environment: GENESIS;
Model Concept(s): Detailed Neuronal Models; Rebound firing;
Search NeuronDB for information about:  I Na,t; I A; I K; I K,Ca; I_Ks;
// This script runs a protocol which
// gives rise to a rebound spike after
// an initial inhibition has been removed

float PI = 3.141592654

int	i
float dt = 1e-5
float sim_time = 1
setclock 0 {dt}
setclock 1 0.0001
setmethod 11
//setmethod 0

float NMDA=0.0
float AMPA = 0;
float Kainate=0.0

float Vrest	= -0.07

include library
include finish

make_cell cell.p neuron

str comp
foreach comp ({el /neuron/##[OBJECT=compartment]})
  setfield {comp} Em -0.058
  setfield {comp} initVm -0.058

include xout_rebound

// if hsolve is used
call /neuron SETUP


float	I
float Imax = {3.14159};
step 0.010 -t
setfield /neuron/soma inject -0.3e-9
step 0.200 -t 
setfield /neuron/soma inject 0
step 0.6 -t

Loading data, please wait...