setuptime = startsw()
one_tenth_ncell = 1
use_gap = 0
use_ectopic = 0
use_inject = 0
default_delay=.05
awake = 1
use_load_balance = 0
{load_file("nrngui.hoc")}
{load_file("fortmap.hoc")}
{load_file("hoc/parlib.hoc")}
focus = 1
iterator pcitr() {local i1, i2
$&1 = 0
$&2 = focus
iterator_statement
}
proc gid_distribute() {
print "gid_distribute ", focus
pc.set_gid2node(focus, pc.id)
}
{load_file("finit.hoc")}
ranseedbase = 1
serial = 0 // override serial set in parlib.hoc
pmesg = 1 && (pc.id == 0)
small_model = 0 // 0 for full model, set to 1 for 40 cells each type
use_traubexact = 1
{load_file("hoc/traubcon.hoc")}
// turn off/on all tables
proc activate_tables() {
usetable_ar = $1
usetable_cal = $1
usetable_cat_a = $1
usetable_cat = $1
usetable_k2 = $1
usetable_ka = $1
usetable_ka_ib = $1
usetable_kc = $1
usetable_kc_fast = $1
usetable_kdr = $1
usetable_kdr_fs = $1
usetable_km = $1
// usetable_naf2 = $1
// usetable_naf = $1
// usetable_naf_tcr = $1
usetable_nap = $1
// usetable_napf = $1
// usetable_napf_spinstell = $1
// usetable_napf_tcr = $1
}
// til the shift bug in the mod files are fixed (table depends on range variable)
if (1) {
usetable_naf2 = 0
usetable_naf = 0
usetable_naf_tcr = 0
usetable_napf = 0
usetable_napf_spinstell = 0
usetable_napf_tcr = 0
}
gfac_AMPA = 1
gfac_NMDA = 0
gfac_GABAA = 1
{load_file("cell_templates.hoc")}
use_p2c_net_connections = 1
{load_file("net/network_specification_interface.hoc")}
if (!serial) {load_file("hoc/parlib2.hoc")}
{load_file("net/serial_or_par_wrapper.hoc")}
objref fihprog_
objref pattern_, tvec_, idvec_
objref cell, typeflag
load_file("clear.hoc")
typeflag = new Vector(14)
pattern_ = new PatternStim()
proc pattern() {
clipboard_retrieve("out.spk")
tvec_ = hoc_obj_[1].c
idvec_ = hoc_obj_[0].c
pattern_.play(tvec_, idvec_)
}
proc fakeout() {local i, gid, th
if ($1 != 0) { th = 1e9 } else { th = 0 }
pattern_.fake_output = $1
for pcitr (&i, &gid) {
pnm.pc.threshold(gid, th)
}
}
proc reload() {local i, st, dtsav localobj ncl
dtsav=dt
st = startsw()
clear()
focus = $1
load_file(1, "net/groucho.hoc")
define_shape()
want_all_spikes()
mkhist(50)
if (pc.id == 0) fihprog_ = new FInitializeHandler("progress()")
if (use_traubexact) {
load_file("hoc/traubcon_net.hoc")
reset_connection_coefficients()
}
st = startsw() - st
cell = cells.object(0)
fakeout(1)
typeflag.fill(0) typeflag.x[cell.type] = 1
dt=dtsav
ncl = pnm.nclist
for i=0, ncl.count-1 if (ncl.object(i).delay == .05) ncl.object(i).delay=0
if (pc.id == 0) {print "reload time: ", st }
}
reload(focus)
proc progress() {
// print "t=",t
cvode.event(t+1, "progress()")
}
cvode_active(1)
setuptime = startsw() - setuptime
if (pc.id == 0) {print "SetupTime: ", setuptime}
steps_per_ms = 50
dt = .01
secondorder = 2
if (serial) {
tstop = 10
}else{
tstop = 10
}
load_file("gidcell.ses")
tf = 100
objref gm, synmat[3]
proc rdat() {local numcomp localobj s, f
s = new String()
classname(cell, s.s)
sprint(s.s, "../p2c/data/GROUCHO110.%s", s.s)
print s.s
// gm = new Matrix(999,8)
gm = new Matrix(10*tf-1,2)
f = new File()
f.ropen(s.s)
gm.scanf(f, gm.nrow, gm.ncol)
gm.getcol(1).line(Graph[0], gm.getcol(0), 2, 1)
if (0) {
gm.getcol(5).line(Graph[1], gm.getcol(0), 2, 1)
gm.getcol(6).line(Graph[1], gm.getcol(0), 3, 1)
gm.getcol(7).line(Graph[1], gm.getcol(0), 4, 1)
}
if (1) {
f = new File()
numcomp=0 forsec cell.all numcomp += 1
synmat[2] = new Matrix(10*tf-1, numcomp+1)
classname(cell, s.s)
sprint(s.s, "../p2c/data/gaba_%s.dat", s.s)
f.ropen(s.s)
synmat[2].scanf(f, synmat[2].nrow, synmat[2].ncol)
synmat[0] = new Matrix(10*tf-1, numcomp+1)
classname(cell, s.s)
sprint(s.s, "../p2c/data/ampa_%s.dat", s.s)
f.ropen(s.s)
synmat[0].scanf(f, synmat[0].nrow, synmat[0].ncol)
synmat[1] = new Matrix(10*tf-1, numcomp+1)
classname(cell, s.s)
sprint(s.s, "../p2c/data/nmda_%s.dat", s.s)
f.ropen(s.s)
synmat[1].scanf(f, synmat[0].nrow, synmat[0].ncol)
}
}
rdat()
pattern()
proc another() {
reload($1)
Graph[0].erase
rdat()
}
//clipboard_retrieve("../p2c/data/ampa.dat")
//hoc_obj_.line(Graph[1], hoc_obj_[1], 2, 1)
//clipboard_retrieve("../p2c/data/nmda.dat")
//hoc_obj_.line(Graph[1], hoc_obj_[1], 2, 1)
objref gg
gg = Graph[1]
which = 1
func am() {local g
g = 0
forsec cell.all if (ismembrane("ampa1_ion")) {
g += iampa1*area(0.5)/100
}
return g
}
func nm() {local g
g = 0
forsec cell.all if (ismembrane("nmda1_ion")) {
g += inmda1*area(0.5)/100
}
return g
}
func ga() {local g
g = 0
forsec cell.all if (ismembrane("gaba1_ion")) {
g += igaba1*area(0.5)/100
}
return g
}
func f() {local g
// cell.comp[which] if (ismembrane("ampa1_ion")) {
// g = iampa1*area(0.5)/100
cell.comp[which] if (ismembrane("gaba1_ion")) {
g = igaba1*area(0.5)/100
}
return g
}
proc pw() {
gg.erase()
which = $1
gm = $o2
gm.getcol(which).line(gg, gm.getcol(0), 2, 1)
}
/* some useful idioms
objref a
a = cell.synlist
for i=0, a.count-1 if (a.o(i).comp == 3) print i, a.o(i), a.o(i).srcgid
objref b
b = pnm.nclist
for i=0,b.count-1 if (b.o(i).syn.comp == 3) print i, b.o(i), b.o(i).syn
for i=0,b.count-1 b.o(i).threshold = 1000
*/
proc mk_another_panel() {local i localobj s1, s2, base
s1 = new String()
s2 = new String()
base = new Vector(14)
base.x[0] = 1
for i=0, 12 {
sprint(s1.s, "hoc_ac_ = num_%s", typename[i].s)
execute(s1.s)
base.x[i+1] = base.x[i] + hoc_ac_
}
xpanel("Make a different cell")
for i=0, 13 {
sprint(s2.s, "another(%d)", base.x[i])
sprint(s1.s, "%s %d", typename[i].s, base.x[i])
xcheckbox(s1.s, &typeflag.x[i], s2.s)
}
xpanel(0)
}
mk_another_panel()
seewhich = 0
seetype = 0 // ampa,nmda,gaba
objref syntrajeclist[3], tsyn
proc synsim() { local i, j localobj vv, gn, gf, r, rr
for i=0,2 { syntrajeclist[i] = new List() }
gn = syntrajeclist[seetype]
gf = synmat[seetype]
i = 1
tsyn = new Vector()
cell.comp[1] {tsyn.record(&t)}
for i=1, gf.ncol-1 cell.comp[i] {
insert ampa1_ion
insert gaba1_ion
insert nmda1_ion
vv = new Vector()
vv.record(&iampa1(.5))
syntrajeclist[0].append(vv)
vv = new Vector()
vv.record(&inmda1(.5))
syntrajeclist[1].append(vv)
vv = new Vector()
vv.record(&igaba1(.5))
syntrajeclist[2].append(vv)
}
stdinit()
continuerun(100)
rr = new Vector()
for i=1, gf.ncol-1 cell.comp[i] for j=0, 2{
syntrajeclist[j].object(i-1).mul(area(0.5)/100)
}
for i=0, gn.count-1 {
r = gn.object(i).c.interpolate(gf.getcol(0), tsyn)
rr.append(r.sub(gf.getcol(i+1)).sumsq)
}
i = rr.max_ind
print i, rr.x[i]
see(i+1, seetype)
}
proc see() {localobj gn, gf, s
s = new String()
gg.erase_all()
seewhich = $1
seetype = $2
if (seetype > 2) {seetype = 2}
if (seetype < 0) {seetype = 0}
gf = synmat[seetype]
gn = syntrajeclist[seetype]
if (seewhich > gn.count) {seewhich = gn.count-1}
if (seewhich < 1) { seewhich = 1 }
if (seetype == 0) { s.s = "AMPA" }
if (seetype == 1) { s.s = "NMDA" }
if (seetype == 2) { s.s = "GABAA" }
cell.comp[seewhich] { sprint(s.s,"%s at %s",s.s, secname()) }
gg.label(.5,.8,s.s,2,1,0,0,1)
gf.getcol(seewhich).line(gg, gf.getcol(0), 2, 1)
gn.object(seewhich-1).line(gg, tsyn)
}
proc mksee() {
xpanel("compare synapse conductance")
xvalue("AMPA=0 NMDA=1 GABAA=2", "seetype", 1, "see(seewhich, seetype)")
xvalue("which", "seewhich", 1, "see(seewhich, seetype)")
xpanel()
}
load_file("vclampg.hoc")
