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Studies of stimulus parameters for seizure disruption using NN simulations (Anderson et al. 2007)
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Accession:
98902
Architecturally realistic neocortical model using seven classes of excitatory and inhibitory single compartment Hodgkin-Huxley cells. Wiring is adapted to minicolumn hypothesis and incorporates visual and neocortical data. Simulation demonstrates spontaneous bursting onset and cessation, and activity can be altered with external electric field.
Reference:
1 .
Anderson WS, Kudela P, Cho J, Bergey GK, Franaszczuk PJ (2007) Studies of stimulus parameters for seizure disruption using neural network simulations.
Biol Cybern
97
:173-94
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Brain Region(s)/Organism:
Cell Type(s):
Neocortex L5/6 pyramidal GLU cell;
Neocortex L2/3 pyramidal GLU cell;
Neocortex V1 interneuron basket PV GABA cell;
Neocortex fast spiking (FS) interneuron;
Channel(s):
I A;
I K;
I K,leak;
I K,Ca;
I Sodium;
I Calcium;
Gap Junctions:
Receptor(s):
AMPA;
Gaba;
Gene(s):
Transmitter(s):
Simulation Environment:
C or C++ program;
Model Concept(s):
Bursting;
Epilepsy;
Vision;
Implementer(s):
Search NeuronDB
for information about:
Neocortex L5/6 pyramidal GLU cell
;
Neocortex L2/3 pyramidal GLU cell
;
Neocortex V1 interneuron basket PV GABA cell
;
AMPA
;
Gaba
;
I A
;
I K
;
I K,leak
;
I K,Ca
;
I Sodium
;
I Calcium
;
/
HopkinsModel
readme.txt
0.cfg
0.net
0.par
*
Other models using 0.par:
Network model with neocortical architecture (Anderson et al 2007,2012; Azhar et al 2012)
0.stim
0.sub
clust_cn.c
clust_cn.h
*
Other models using clust_cn.h:
Network model with neocortical architecture (Anderson et al 2007,2012; Azhar et al 2012)
crl.c
*
Other models using crl.c:
Network model with neocortical architecture (Anderson et al 2007,2012; Azhar et al 2012)
jhist.c
*
Other models using jhist.c:
Network model with neocortical architecture (Anderson et al 2007,2012; Azhar et al 2012)
link_sort.c
*
Other models using link_sort.c:
Network model with neocortical architecture (Anderson et al 2007,2012; Azhar et al 2012)
lnet.h
Makefile
mkhist.c
*
Other models using mkhist.c:
Network model with neocortical architecture (Anderson et al 2007,2012; Azhar et al 2012)
mklink.c
mknode.c
mkpar.c
*
Other models using mkpar.c:
Network model with neocortical architecture (Anderson et al 2007,2012; Azhar et al 2012)
netclustwacnmdadiff.c
rnetcolumn
sublink.c
*
Other models using sublink.c:
Network model with neocortical architecture (Anderson et al 2007,2012; Azhar et al 2012)
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