: $Id: ntIh.mod,v 1.6 1998/08/14 20:52:38 billl Exp $ TITLE anomalous rectifier channel : : Anomalous Rectifier Ih - cation (Na/K) channel for geniculate interneurons : Differential equations : : : Written by Jun Zhu, Univ. Wisconsin, Jan 1996 : INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)} NEURON { SUFFIX iar USEION other WRITE iother VALENCE 1 RANGE ghbar, shift GLOBAL h_inf, tau_h, erev, stp } UNITS { (molar) = (1/liter) (mM) = (millimolar) (mA) = (milliamp) (mV) = (millivolt) (msM) = (ms mM) } PARAMETER { v (mV) erev = -44 (mV) celsius = 36 (degC) ghbar = .0008 (mho/cm2) shift = -6 (mV) stp = 7.4 } STATE { h } ASSIGNED { i (mA/cm2) iother (mA/cm2) h_inf tau_h (ms) tadj } BREAKPOINT { SOLVE state METHOD cnexp iother = ghbar * h * (v - erev) } DERIVATIVE state { evaluate_fct(v) h' = (h_inf - h) / tau_h } UNITSOFF INITIAL { tadj = 3.0 ^ ((celsius-36)/10) evaluate_fct(v) h = h_inf : Experiments of Coulter et al were at 36 deg.C : Q10 is assumed equal to 3 : } PROCEDURE evaluate_fct(v (mV)) { h_inf = 1 / ( 1 + exp((v+shift+79)/stp) ) tau_h = exp((v+shift+293.3)/29.67) / ( 1 + exp((v+shift+76.7)/7.82)) / tadj } UNITSON