This is the readme for the model associated with the paper

Severi S, Corsi C, Rocchetti M, Zaza A (2009) Mechanisms of
beta-adrenergic modulation of I(Ks) in the guinea-pig ventricle:
insights from experimental and model-based analysis.
Biophys J 96:3862-72

This simulink code is provided in an as-is state by Stefano Severi.
Parameters are set to reproduce the current response to a single
voltage step in control conditions.

Start matlab and type


on the command line to load initial conditions and the simulink model:

simulink picture displays here (when works)

Select Simulation->Run in simulink, and then create a figure to see
the result: