// SPN neuron model // --------------------------------------------- // // This model simulates rebound action potential firing in SPN neurons // following prolonged inhibition from the MNTB. // // Reference: // The Sound of Silence: ionic mechanisms encoding sound termination. // Cornelia Kopp-Scheinpflug, Adam JB Tozer, Susan W Robinson // Bruce L Tempel, Matthias H Hennig and Ian D Forsythe // Neuron, in press (2011) // // Contact: // Matthias H. Hennig, University of Edinburgh, 2011 // m.hennig@ed.ac.uk // mhhennig@gmail.com // // with contributions from: // Sarah J. Griffin, MRC Toxicology Unit, Leicester {soma input = new PointProcessManager(0)} {object_push(input)} {mt.select("TriggeredIClamp") i = mt.selected() ms[i] = new MechanismStandard("TriggeredIClamp") ms[i].set("dur", 100, 0) ms[i].set("amp", -0, 0) mt.select("TriggeredIClamp") i = mt.selected() maction(i) hoc_ac_ = 0.5 sec.sec move() d1.flip_to(0)} {object_pop() doNotify()} {input = input.v1} objref input {soma input = new PointProcessManager(0)} {object_push(input)} {mt.select("NetStim") i = mt.selected() ms[i] = new MechanismStandard("NetStim") ms[i].set("interval", 10, 0) ms[i].set("number", 10, 0) ms[i].set("start", 1000, 0) // 500 ms[i].set("noise", 0, 0) mt.select("NetStim") i = mt.selected() maction(i) hoc_ac_ = 0.5 sec.sec move() d1.flip_to(0)} {object_pop() doNotify()} {input = input.v1} objref input ns = new NetCon(NetStim[0], TriggeredIClamp[0], 0,0,0)