TITLE Na persistent channel : used in distal oblique dendrites to assist Ca spike initiation : a typo in the exponential function was pointed out by Michele Migliore and : corrected by Yiota Poirazi on December 4th, 2003 NEURON { SUFFIX nap USEION na READ ena WRITE ina RANGE gnabar,vhalf, K, g, gmax } UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { : parameters that can be entered when function is called in cell-setup v (mV) ena = 50 (mV) : Na reversal potential (reset in cell-setup.hoc) K = 1 (mV) : slope of steady state variable : gnabar = 0.001e-2 (mho/cm2) : suggested conductance, 1 percent of the transient Na current gnabar = 0 (mho/cm2) : initialized conductance vhalf = -51.90 (mV) : half potential } STATE { n } ASSIGNED { ina (mA/cm2) g (mho/cm2) gmax (mho/cm2) } INITIAL { : SOLVE states not used gmax = 0 } BREAKPOINT { states(v) g = gnabar*n*n*n ina = g*(v-ena) if (g > gmax) { gmax = g } } PROCEDURE states(v (mV)) { : exact when v held constant; integrates over dt step : n = 1 / (1 + (exp(vhalf - v))/K) : steady state value !!!typo in the exponential function!!! TABLE n DEPEND vhalf, K FROM -150 TO 150 WITH 300 n = 1 / (1 + exp((vhalf - v)/K)) : steady state value }