load_file("E807.hoc") /******************************************************************/ // Insert passive & active conductances /******************************************************************/ Vrest = -70 ins_pasive() ins_active() mesh_init() /******************************************************************/ // Main Setup for EPSP /******************************************************************/ // Setup synapse Ndsyn = 1 //No of syn to be stim'd NAratio = 0.2 // NMDA-to-AMPA ratio atau = 1.5 // Rise time of I_AMPA ntau = 16 // decay tau of Inmda tauD = 100 // Recovery of RRP in ms tauF = 50 // decay of Af in ms p0 = 0.2 // basal rls prob. Af = 1 // postAP facilitation inc / pb // taudmf = 20 taufmf = 100 p0mf = 0.05 Afmf = 2 // ns = new NetStim(0.5) ns.start = 10 //StimInit ns.number = 1 //StimN ns.interval = 20 //StimIntv, 50 Hz tstop = 4*ns.start + ns.number * ns.interval + 500 // wt[1] = 5.0e-4/p0mf // MF, atau*1 wt[2] = 1.0e-4/p0 // AC, atau*1 wt[3] = 1.9e-4/p0 // PP, atau*1 /******************************************************************/ // Run EPSP /******************************************************************/ // Ndsyn = 1 synloc = 3 // PP wtstep = 0.5e-4/p0 // gheight = 20 // graph height in mV graphepsp() gepsp.begin() setupsynapse(0) // control condkd(1) condNa(1) for(nsyn=1; nsyn<9; nsyn+=1) { wt[synloc] = wtstep*nsyn runsyn(synloc, 1) //run(synloc, overlap) }