:Comment : The transient component of the K current :Reference : : Voltage-gated K+ channels in layer 5 neocortical pyramidal neurones from young rats:subtypes and gradients,Korngreen and Sakmann, J. Physiology, 2000 :Comment : shifted -10 mv to correct for junction potential :Comment: corrected rates using q10 = 2.3, target temperature 34, orginal 21 NEURON { SUFFIX K_Tst USEION k READ ek WRITE ik RANGE gK_Tstbar, gK_Tst, ik, offm, slom, offh, sloh, offmt, slomt, taummin, taumdiff,offht, sloht, tauhmin, tauhdiff } UNITS { (S) = (siemens) (mV) = (millivolt) (mA) = (milliamp) } PARAMETER { gK_Tstbar = 0.00001 (S/cm2) offm = -10 (mV) slom = 19 (mV) offh = -76 (mV) sloh = 10 (mV) offmt = -81 (mV) slomt = 59 (mV) taummin = 0.34 (ms) taumdiff = 0.92 (ms) offht = -83 (mV) sloht = 23 (mV) tauhmin = 8 (ms) tauhdiff = 49 (ms) } ASSIGNED { v (mV) ek (mV) ik (mA/cm2) gK_Tst (S/cm2) mInf mTau hInf hTau } STATE { m h } BREAKPOINT { SOLVE states METHOD cnexp gK_Tst = gK_Tstbar*(m^4)*h ik = gK_Tst*(v-ek) } DERIVATIVE states { rates() m' = (mInf-m)/mTau h' = (hInf-h)/hTau } INITIAL{ rates() m = mInf h = hInf } PROCEDURE rates(){ LOCAL qt qt = 2.3^((34-21)/10) UNITSOFF mInf = 1/(1 + exp((offm-v)/slom)) hInf = 1/(1 + exp(-(offh-v)/sloh)) mTau = (taummin+taumdiff*exp(-((offmt-v)/slomt)^2))/qt hTau = (tauhmin+tauhdiff*exp(-((offht-v)/sloht)^2))/qt UNITSON }