I Hepburn, A Jain, H Gangal, Y Yamamoto, K Tanaka-Yamamoto and Erik De Schutter (2017) A model of induction of cerebellar Long-Term Depression including RKIP inactivation of Raf and MEK. Frontiers in Molecular Neuroscience 10(19) doi: 10.3389/fnmol.2017.00019 The command line arguments can be used to control the simulations so as to gather data as plotted in the publication, for example to vary calcium input and to vary PKC number. Command line arguments are also used to specify what data to record and (optionally) to plot. The usage of command line arguments is described further within the simulation script. Please refer to the STEPS website for more information about the simulation environment and installation instructions: http://steps.sourceforge.net Python dependencies to run this script: Numpy, SciPy, Matplotlib.