:Comment : The persistent component of the K current :Reference : : Voltage-gated K+ channels in layer 5 neocortical pyramidal neurones from young rats:subtypes and gradients,Korngreen and Sakmann, J. Physiology, 2000 :Comment : shifted -10 mv to correct for junction potential :Comment: corrected rates using q10 = 2.3, target temperature 34, orginal 21 NEURON { SUFFIX K_Pst USEION k READ ek WRITE ik RANGE gK_Pstbar, gK_Pst, ik, offm, slom, offmt, slomt, taummin, taumdiff1, taumdiff2, offh, sloh, offht1, offht2, sloht, tauhmean, tauhdiff1, tauhdiff2 } UNITS { (S) = (siemens) (mV) = (millivolt) (mA) = (milliamp) } PARAMETER { gK_Pstbar = 0.00001 (S/cm2) offm = -11 (mV) slom = 12 (mV) offmt = -10 (mV) slomt = 38.46153846 (mV) taummin = 1.25 (ms) taumdiff1 = 175.03 (ms) taumdiff2 = 13 (ms) offh = -64 (mV) sloh = 11 (mV) offht1 = -65 (mV) offht2 = -85 (mV) sloht = 48 (mV) tauhmean = 360 (ms) tauhdiff1 = 1010 (ms) tauhdiff2 = 24 (ms/mV) } ASSIGNED { v (mV) ek (mV) ik (mA/cm2) gK_Pst (S/cm2) mInf mTau hInf hTau } STATE { m h } BREAKPOINT { SOLVE states METHOD cnexp gK_Pst = gK_Pstbar*m*m*h ik = gK_Pst*(v-ek) } DERIVATIVE states { rates() m' = (mInf-m)/mTau h' = (hInf-h)/hTau } INITIAL{ rates() m = mInf h = hInf } PROCEDURE rates(){ LOCAL qt, thresh qt = 2.3^((34-21)/10) thresh = offmt-slomt/2*log(taumdiff1/taumdiff2) UNITSOFF mInf = (1/(1 + exp((offm-v)/slom))) if(v