b0VIM 7.4Y/Wn(@pablomcstallo-2.local~pablomc/Norway_LGN_2/cortex_neurons/READMEutf-8 U3210#"! UtpuadTDuX*)|X;:  ~ B " !   s 6 5 T S < l 6 _ 0 / . !   H0/|JI32A@rqbaK4Gq*~Dhttp://www.neurhttp://www.neuron.yale.edu/phpbb/viewtopic.php?f=28&t=592IT.mod to cnexp as per20120109 updated SOLVE method in cadecay.mod to derivimplicit and IM.mod,rundemo.hocgui is erased with the restart() procedure which was added toof xopen. Lastly, before the gui for each demo is started the previousbe opened once per NEURON launch are now opened via load_file insteadwas replaced by a radio button panel, and any files which should only3 demos to run in the same NEURON process. Thus the original button panelNote: 3/9/2002 Michael Hines made non-substantive changes to allow the7/11/2005 Changes added which removes electrode on subsequent simulations.http://cns.iaf.cnrs-gif.fremail: Destexhe@iaf.cnrs-gif.frFrance91198 Gif-sur-Yvette, Avenue de la Terrasse,CNRS, UNIC (Bat-33), Alain DestexheFor further information, please contact: http://www.neuro.duke.edu http://www.neuron.yale.edurefer to the following sites:For more information about how to get NEURON and how to install it, pleaseRun Control window. Then click on "Init and Run" button to start the simulation..."Simulations of cortical cells" window. Reposition the windows to find theOnce the menu and graphics interface has appeared, select a simulation from theback to any platform: by clicking on mosinit.hoc in windows explorer. Compile the mechanism (mod) files by using mknrndll. Then start the simulationmswin platform:quit nrngui mosinit.hoc:qThen, execute the main demo program by typing:given in the mod files.the machine you are using. Just type "nrnivmodl" to compile the mechanismsTo compile the demo, NEURON and INTERVIEWS must be installed and working onunix platform::qUse autolaunch on modeldb or: ========== HOW TO RUN cadecay.mod : intracellular calcium dynamics IT.mod : T-type calcium current IM.mod : slow voltage-dependent potassium current (IM) HH2.mod : fast sodium spikes (Na and K currents) ========== MECHANISMSdemo_IN_FS.oc : fast-spiking interneurondemo_PY_LTS.oc : bursting pyramidal neuron (LTS cell)demo_PY_RS.oc : regular-spiking pyramidal neuron ======== and their role in generating spike-and-wave oscillations and their role in generating spike-and-wave oscillationsLTS cells in cerebral cortexlls in cerebral cortex(see electronic copy at http://cns.iaf.cnrs-gif.fr) Neurocomputing 38: 555-563, 2001. and their role in generating spike-and-wave oscillations. Destexhe A, Contreras D and Steriade M. LTS cells in cerebral cortex thalamic relay cells. J. Neurophysiol. 79: 999-1016, 1998. synchronizing action of corticothalamic feedback through inhibition of Destexhe A, Contreras D and Steriade M. Mechanisms underlying the See also the original paper: Oxford University Press, 2001 Destexhe A and Sejnowski TJ. Thalamocortical Assemblies.kinetics of currents are given in:simulate single-compartment models of cortical neurons. Details of theThe package contains mechanisms (.mod files) and programs (.oc files) needed to http://www.neuron.yale.eduHines and available on internet at:This package is running with the NEURON simulation program written by Michael http://cns.iaf.cnrs-gif.fr Destexhe@iaf.cnrs-gif.fr 91198 Gif-sur-Yvette, France CNRS, UNIC (Bat-33), Avenue de la Terrasse, Alain Destexhe NEURON DEMO FOR SIMULATING DIFFERENT CLASSES OF CORTICAL NEURONS