: Dynamics that track inside calcium concentration : modified from Destexhe et al. 1994 NEURON { SUFFIX CaDynamics_E2 USEION ca READ ica WRITE cai RANGE decay, gamma, minCai, depth } UNITS { (mV) = (millivolt) (mA) = (milliamp) FARADAY = (faraday) (coulombs) (molar) = (1/liter) (mM) = (millimolar) (um) = (micron) } PARAMETER { gamma = 0.05 : percent of free calcium (not buffered) decay = 80 (ms) : rate of removal of calcium depth = 0.1 (um) : depth of shell minCai = 1e-4 (mM) } ASSIGNED {ica (mA/cm2)} STATE { cai (mM) } BREAKPOINT { SOLVE states METHOD cnexp } DERIVATIVE states { cai' = -(10000)*(ica*gamma/(2*FARADAY*depth)) - (cai - minCai)/decay }