TITLE Ampa synapse COMMENT simple alpha-synapse that generates a single PSP ********************************************* reference: McCormick, Wang & Huguenard (1993) Cerebral Cortex 3(5), 387-398 ********************************************* Assembled for MyFirstNEURON by Arthur Houweling ENDCOMMENT INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)} NEURON { POINT_PROCESS AmpaSynapse RANGE onset, gmaxEPSP, e, i, g, w NONSPECIFIC_CURRENT i } UNITS { (nA) = (nanoamp) (mV) = (millivolt) (nS) = (nanomho) } PARAMETER { onset (ms) gmaxEPSP= 0 (nS) w= 1 : weight factor for gmaxEPSP e= 0.0 (mV) v (mV) celsius (degC) } ASSIGNED { i (nA) g (nS) tadj } UNITSOFF INITIAL { tadj = 3^((celsius-23.5)/10) } BREAKPOINT { LOCAL tt tt= (t-onset)*tadj if (t>onset && tt<1630) { g = w*gmaxEPSP * exp(-tt/18) * (1-exp(-tt/2.2))/0.68 } else {g = 0} i = g * (v - e) } UNITSON