// Trying to open ../diagnostic/tstop.dat // new end time timtot = 150. // Trying to open ../diagnostic/dt_F.dat // new dt = 0.002 // i, neigh(i, (1, 2, 3, 4)) // 1 54 2 15 28 41 // 2 1 3 4 0 0 // 3 2 4 5 6 0 // 4 2 3 7 0 0 // 5 3 6 8 0 0 // 6 3 5 9 0 0 // 7 4 10 0 0 0 // 8 5 11 0 0 0 // 9 6 0 0 0 0 // 10 7 0 0 0 0 // 11 8 12 0 0 0 // 12 11 13 0 0 0 // 13 12 14 0 0 0 // 14 13 0 0 0 0 // 15 1 16 17 0 0 // 16 15 17 18 19 0 // 17 15 16 20 0 0 // 18 16 19 21 0 0 // 19 16 18 22 0 0 // 20 17 23 0 0 0 // 21 18 24 0 0 0 // 22 19 0 0 0 0 // 23 20 0 0 0 0 // 24 21 25 0 0 0 // 25 24 26 0 0 0 // 26 25 27 0 0 0 // 27 26 0 0 0 0 // 28 1 29 30 0 0 // 29 28 30 31 32 0 // 30 28 29 33 0 0 // 31 29 32 34 0 0 // 32 29 31 35 0 0 // 33 30 36 0 0 0 // 34 31 37 0 0 0 // 35 32 0 0 0 0 // 36 33 0 0 0 0 // 37 34 38 0 0 0 // 38 37 39 0 0 0 // 39 38 40 0 0 0 // 40 39 0 0 0 0 // 41 1 42 43 0 0 // 42 41 43 44 45 0 // 43 41 42 46 0 0 // 44 42 45 47 0 0 // 45 42 44 48 0 0 // 46 43 49 0 0 0 // 47 44 50 0 0 0 // 48 45 0 0 0 0 // 49 46 0 0 0 0 // 50 47 51 0 0 0 // 51 50 52 0 0 0 // 52 51 53 0 0 0 // 53 52 0 0 0 0 // 54 1 55 0 0 0 // 55 54 56 58 0 0 // 56 55 57 58 0 0 // 57 56 0 0 0 0 // 58 55 56 59 0 0 // 59 58 0 0 0 0 /* deepbask/deepbask_template.hoc automatically written from f2nrn/neuron_code_writer.f via subroutines that were inserted into the fortran code e.g., deepbask/integrate_deepbask.hoc The template's form was derived by Tom Morse and Michael Hines from a template, pyr3_template created by Roger Traub and Maciej Lazarewicz when they ported Traub RD, Buhl EH, Gloveli T, Whittington MA. Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na(+) Conductance or by Blocking BK Channels.J Neurophysiol. 2003 Feb;89(2):909-21. to NEURON */ begintemplate deepbask public type // parts of the template were lifted from a default // cell writing from Network Builder NetGUI[0] public is_art public init, topol, basic_shape, subsets public geom, biophys public synlist, x, y, z, position public connect2target public set_netcon_src_comp // the above function added to set neton // compartment source in the presyn cell public comp, level, Soma, Dendrites public Soma_Dendrites, Axon, all public presyn_comp, top_level // it is the responsibility of the calling // program to set the above presynaptic // compartment number external traub_connect objref this create comp[ 59+1] objref level[ 9+1], Soma, Dendrites objref Soma_Dendrites, Axon objref synlist func type() {return 9 } proc init() { doubler = 1 comp[0] delete_section() // clean up for fortran code traub_connect( 59+1) titlePrint() presyn_comp = 59 // in Traub model;changed by calling prog. objref Soma, Axon, Dendrites, Soma_Dendrites objref level topol() shape() geom() // the geometry and subsets() // subsets and biophys() // active currents synlist = new List() // list of synapses // NetGUI[0] stores synapses in the cell object, in // Traub model it is easier to store them outside set_doubler() // to double or not if (doubler) {double_dend_cond()} /* for taking spine membrane area correction into account (the method used doubles max cond's when spines present) */ more_adjustments() } proc double_dend_cond() { /* this function gets replaced later with another one if double_dend_cond() is tacked on. */ } proc titlePrint() { /* print " print "-----" print " print "deepbask Neuron Model based on " print "Traub RD et al (2005, 2003)" print " print "-----" Remove title printing with this comment for now. Printing otherwise repeats (for each cell) -too voluminous for a network creation */ } proc set_doubler() {doubler=0} // this function gets replaced with one that // sets doubler to 0 when there are no spines // in the cell (for no spines the additional // hoc code is written from integrate_cell.f // where cell is nRT, TCR. Woops I just // found that deepaxax, deepbask, deepLTS, // supaxax, supbask, supLTS all use the script // cell/run_fortran.sh to replace the =1's with // =0's. I will change the fortran code to // make it all run_fortran.sh replacements or // not for uniformity. proc topol() { // create comp[ 60] // note one greater than numcomp due to fortran indicies // last argument, parent location for connection // is overwritten to 1 for parents with connected children // in below traub_connect proc calls traub_connect(this, 1, 54, 0.0611490233, 0) traub_connect(this, 1, 2, 0.0873746044, 1) traub_connect(this, 1, 15, 0.0873746044, 1) traub_connect(this, 1, 28, 0.0873746044, 1) traub_connect(this, 1, 41, 0.0873746044, 1) traub_connect(this, 2, 3, 0.0250126876, 1) traub_connect(this, 2, 4, 0.0250126876, 1) traub_connect(this, 3, 4, 0.0174532778, 1) traub_connect(this, 3, 5, 0.00988321907, 1) traub_connect(this, 3, 6, 0.00988321907, 1) traub_connect(this, 4, 7, 0.0174532778, 1.) traub_connect(this, 5, 6, 0.00689334805, 1) traub_connect(this, 5, 8, 0.00689334805, 1.) traub_connect(this, 6, 9, 0.00689334805, 1.) traub_connect(this, 7, 10, 0.0174532778, 1.) traub_connect(this, 8, 11, 0.00689334805, 1.) traub_connect(this, 11, 12, 0.00689334805, 1.) traub_connect(this, 12, 13, 0.00689334805, 1.) traub_connect(this, 13, 14, 0.00689334805, 1.) traub_connect(this, 15, 16, 0.0250126876, 1) traub_connect(this, 15, 17, 0.0250126876, 1) traub_connect(this, 16, 17, 0.0174532778, 1) traub_connect(this, 16, 18, 0.00988321907, 1) traub_connect(this, 16, 19, 0.00988321907, 1) traub_connect(this, 17, 20, 0.0174532778, 1.) traub_connect(this, 18, 19, 0.00689334805, 1) traub_connect(this, 18, 21, 0.00689334805, 1.) traub_connect(this, 19, 22, 0.00689334805, 1.) traub_connect(this, 20, 23, 0.0174532778, 1.) traub_connect(this, 21, 24, 0.00689334805, 1.) traub_connect(this, 24, 25, 0.00689334805, 1.) traub_connect(this, 25, 26, 0.00689334805, 1.) traub_connect(this, 26, 27, 0.00689334805, 1.) traub_connect(this, 28, 29, 0.0250126876, 1) traub_connect(this, 28, 30, 0.0250126876, 1) traub_connect(this, 29, 30, 0.0174532778, 1) traub_connect(this, 29, 31, 0.00988321907, 1) traub_connect(this, 29, 32, 0.00988321907, 1) traub_connect(this, 30, 33, 0.0174532778, 1.) traub_connect(this, 31, 32, 0.00689334805, 1) traub_connect(this, 31, 34, 0.00689334805, 1.) traub_connect(this, 32, 35, 0.00689334805, 1.) traub_connect(this, 33, 36, 0.0174532778, 1.) traub_connect(this, 34, 37, 0.00689334805, 1.) traub_connect(this, 37, 38, 0.00689334805, 1.) traub_connect(this, 38, 39, 0.00689334805, 1.) traub_connect(this, 39, 40, 0.00689334805, 1.) traub_connect(this, 41, 42, 0.0250126876, 1) traub_connect(this, 41, 43, 0.0250126876, 1) traub_connect(this, 42, 43, 0.0174532778, 1) traub_connect(this, 42, 44, 0.00988321907, 1) traub_connect(this, 42, 45, 0.00988321907, 1) traub_connect(this, 43, 46, 0.0174532778, 1.) traub_connect(this, 44, 45, 0.00689334805, 1) traub_connect(this, 44, 47, 0.00689334805, 1.) traub_connect(this, 45, 48, 0.00689334805, 1.) traub_connect(this, 46, 49, 0.0174532778, 1.) traub_connect(this, 47, 50, 0.00689334805, 1.) traub_connect(this, 50, 51, 0.00689334805, 1.) traub_connect(this, 51, 52, 0.00689334805, 1.) traub_connect(this, 52, 53, 0.00689334805, 1.) traub_connect(this, 54, 55, 0.026078893, 1.) traub_connect(this, 55, 56, 0.0185405311, 1) traub_connect(this, 55, 58, 0.0185405311, 1) traub_connect(this, 56, 57, 0.01570795, 1.) traub_connect(this, 56, 58, 0.01570795, 1) traub_connect(this, 58, 59, 0.01570795, 1.) access comp[1] // handy statement if want to start gui's from nrnmainmenu } proc geom() { // the "traub level" subsets are created and defined below top_level = 9 objref level[top_level+1] for i=0,top_level { level[i] = new SectionList() } comp[ 1] { level[ 1].append() L= 20. diam = 2* 7.5 } comp[ 2] { level[ 2].append() L= 40. diam = 2* 1.06 } comp[ 3] { level[ 3].append() L= 40. diam = 2* 0.666666667 } comp[ 4] { level[ 3].append() L= 40. diam = 2* 0.666666667 } comp[ 5] { level[ 4].append() L= 40. diam = 2* 0.418972332 } comp[ 6] { level[ 4].append() L= 40. diam = 2* 0.418972332 } comp[ 7] { level[ 4].append() L= 40. diam = 2* 0.666666667 } comp[ 8] { level[ 5].append() L= 40. diam = 2* 0.418972332 } comp[ 9] { level[ 5].append() L= 40. diam = 2* 0.418972332 } comp[ 10] { level[ 5].append() L= 40. diam = 2* 0.666666667 } comp[ 11] { level[ 6].append() L= 40. diam = 2* 0.418972332 } comp[ 12] { level[ 7].append() L= 40. diam = 2* 0.418972332 } comp[ 13] { level[ 8].append() L= 40. diam = 2* 0.418972332 } comp[ 14] { level[ 9].append() L= 40. diam = 2* 0.418972332 } comp[ 15] { level[ 2].append() L= 40. diam = 2* 1.06 } comp[ 16] { level[ 3].append() L= 40. diam = 2* 0.666666667 } comp[ 17] { level[ 3].append() L= 40. diam = 2* 0.666666667 } comp[ 18] { level[ 4].append() L= 40. diam = 2* 0.418972332 } comp[ 19] { level[ 4].append() L= 40. diam = 2* 0.418972332 } comp[ 20] { level[ 4].append() L= 40. diam = 2* 0.666666667 } comp[ 21] { level[ 5].append() L= 40. diam = 2* 0.418972332 } comp[ 22] { level[ 5].append() L= 40. diam = 2* 0.418972332 } comp[ 23] { level[ 5].append() L= 40. diam = 2* 0.666666667 } comp[ 24] { level[ 6].append() L= 40. diam = 2* 0.418972332 } comp[ 25] { level[ 7].append() L= 40. diam = 2* 0.418972332 } comp[ 26] { level[ 8].append() L= 40. diam = 2* 0.418972332 } comp[ 27] { level[ 9].append() L= 40. diam = 2* 0.418972332 } comp[ 28] { level[ 2].append() L= 40. diam = 2* 1.06 } comp[ 29] { level[ 3].append() L= 40. diam = 2* 0.666666667 } comp[ 30] { level[ 3].append() L= 40. diam = 2* 0.666666667 } comp[ 31] { level[ 4].append() L= 40. diam = 2* 0.418972332 } comp[ 32] { level[ 4].append() L= 40. diam = 2* 0.418972332 } comp[ 33] { level[ 4].append() L= 40. diam = 2* 0.666666667 } comp[ 34] { level[ 5].append() L= 40. diam = 2* 0.418972332 } comp[ 35] { level[ 5].append() L= 40. diam = 2* 0.418972332 } comp[ 36] { level[ 5].append() L= 40. diam = 2* 0.666666667 } comp[ 37] { level[ 6].append() L= 40. diam = 2* 0.418972332 } comp[ 38] { level[ 7].append() L= 40. diam = 2* 0.418972332 } comp[ 39] { level[ 8].append() L= 40. diam = 2* 0.418972332 } comp[ 40] { level[ 9].append() L= 40. diam = 2* 0.418972332 } comp[ 41] { level[ 2].append() L= 40. diam = 2* 1.06 } comp[ 42] { level[ 3].append() L= 40. diam = 2* 0.666666667 } comp[ 43] { level[ 3].append() L= 40. diam = 2* 0.666666667 } comp[ 44] { level[ 4].append() L= 40. diam = 2* 0.418972332 } comp[ 45] { level[ 4].append() L= 40. diam = 2* 0.418972332 } comp[ 46] { level[ 4].append() L= 40. diam = 2* 0.666666667 } comp[ 47] { level[ 5].append() L= 40. diam = 2* 0.418972332 } comp[ 48] { level[ 5].append() L= 40. diam = 2* 0.418972332 } comp[ 49] { level[ 5].append() L= 40. diam = 2* 0.666666667 } comp[ 50] { level[ 6].append() L= 40. diam = 2* 0.418972332 } comp[ 51] { level[ 7].append() L= 40. diam = 2* 0.418972332 } comp[ 52] { level[ 8].append() L= 40. diam = 2* 0.418972332 } comp[ 53] { level[ 9].append() L= 40. diam = 2* 0.418972332 } comp[ 54] { level[ 0].append() L= 50. diam = 2* 0.7 } comp[ 55] { level[ 0].append() L= 50. diam = 2* 0.6 } comp[ 56] { level[ 0].append() L= 50. diam = 2* 0.5 } comp[ 57] { level[ 0].append() L= 50. diam = 2* 0.5 } comp[ 58] { level[ 0].append() L= 50. diam = 2* 0.5 } comp[ 59] { level[ 0].append() L= 50. diam = 2* 0.5 } } // Here are some commonly used subsets of sections objref all proc subsets() { local i objref Soma, Dendrites, Soma_Dendrites, Axon objref all Soma = new SectionList() Dendrites = new SectionList() Soma_Dendrites = new SectionList() Axon = new SectionList() for i=1,top_level { forsec level[i] { // recall level 0 is axon, 1 is soma, higher are dends Soma_Dendrites.append() if (i>1) {Dendrites.append()} } } forsec level[1] { Soma.append() } forsec level[0] { Axon.append() } all = new SectionList() for i=1, 59 comp[i] all.append() } proc shape() { /* This section could contain statements like {pt3dclear() pt3dadd(-1,-1,0,1) pt3dadd(-1,-2,0,1)} These visual settings do not effect the electrical and chemical systems of equations. */ } proc biophys() { // // insert the mechanisms and assign max conductances // forsec all { insert pas } // g_pas has two values; soma-dend,axon forsec level[ 0] { insert naf2 gbar_naf2 = 0.4 insert kdr_fs gbar_kdr_fs = 0.4 insert ka gbar_ka = 0.001 insert k2 gbar_k2 = 0.0005 } forsec level[ 1] { insert naf2 gbar_naf2 = 0.06 insert nap gbar_nap = 0.0006 insert kdr_fs gbar_kdr_fs = 0.1 insert kc_fast gbar_kc_fast = 0.025 insert ka gbar_ka = 0.001 insert km gbar_km = 0.0005 insert k2 gbar_k2 = 0.0005 insert kahp_slower gbar_kahp_slower = 0.0001 insert cal gbar_cal = 0.0001 insert cat gbar_cat = 5.E-05 insert ar gbar_ar = 2.5E-05 insert cad // *** ca diffusion: beta=1/tau beta_cad = 0.02 // cafor(I) (FORTRAN) converted to phi (NEURON) phi_cad = 260000. } forsec level[ 2] { insert naf2 gbar_naf2 = 0.06 insert nap gbar_nap = 0.0006 insert kdr_fs gbar_kdr_fs = 0.1 insert kc_fast gbar_kc_fast = 0.025 insert ka gbar_ka = 0.001 insert km gbar_km = 0.0005 insert k2 gbar_k2 = 0.0005 insert kahp_slower gbar_kahp_slower = 0.0001 insert cal gbar_cal = 0.0001 insert cat gbar_cat = 5.E-05 insert ar gbar_ar = 2.5E-05 insert cad // *** ca diffusion: beta=1/tau beta_cad = 0.05 // cafor(I) (FORTRAN) converted to phi (NEURON) phi_cad = 520000. } forsec level[ 3] { insert naf2 gbar_naf2 = 0.06 insert nap gbar_nap = 0.0006 insert kdr_fs gbar_kdr_fs = 0.1 insert kc_fast gbar_kc_fast = 0.025 insert ka gbar_ka = 0.001 insert km gbar_km = 0.0005 insert k2 gbar_k2 = 0.0005 insert kahp_slower gbar_kahp_slower = 0.0001 insert cal gbar_cal = 0.0001 insert cat gbar_cat = 5.E-05 insert ar gbar_ar = 2.5E-05 insert cad // *** ca diffusion: beta=1/tau beta_cad = 0.05 // cafor(I) (FORTRAN) converted to phi (NEURON) phi_cad = 520000. } forsec level[ 4] { insert naf2 gbar_naf2 = 0.01 insert nap gbar_nap = 0.0001 insert kdr_fs gbar_kdr_fs = 0.01 insert kc_fast gbar_kc_fast = 0.025 insert ka gbar_ka = 0.001 insert km gbar_km = 0.0005 insert k2 gbar_k2 = 0.0005 insert kahp_slower gbar_kahp_slower = 0.0001 insert cal gbar_cal = 0.0002 insert cat gbar_cat = 0.002 insert ar gbar_ar = 2.5E-05 insert cad // *** ca diffusion: beta=1/tau beta_cad = 0.05 // cafor(I) (FORTRAN) converted to phi (NEURON) phi_cad = 520000. } forsec level[ 5] { insert naf2 gbar_naf2 = 0.01 insert nap gbar_nap = 0.0001 insert kdr_fs gbar_kdr_fs = 0.01 insert kc_fast gbar_kc_fast = 0.025 insert ka gbar_ka = 0.001 insert km gbar_km = 0.0005 insert k2 gbar_k2 = 0.0005 insert kahp_slower gbar_kahp_slower = 0.0001 insert cal gbar_cal = 0.0002 insert cat gbar_cat = 0.002 insert ar gbar_ar = 2.5E-05 insert cad // *** ca diffusion: beta=1/tau beta_cad = 0.05 // cafor(I) (FORTRAN) converted to phi (NEURON) phi_cad = 520000. } forsec level[ 6] { insert naf2 gbar_naf2 = 0.01 insert nap gbar_nap = 0.0001 insert kdr_fs gbar_kdr_fs = 0.01 insert kc_fast gbar_kc_fast = 0.025 insert ka gbar_ka = 0.001 insert km gbar_km = 0.0005 insert k2 gbar_k2 = 0.0005 insert kahp_slower gbar_kahp_slower = 0.0001 insert cal gbar_cal = 0.0002 insert cat gbar_cat = 0.002 insert ar gbar_ar = 2.5E-05 insert cad // *** ca diffusion: beta=1/tau beta_cad = 0.05 // cafor(I) (FORTRAN) converted to phi (NEURON) phi_cad = 520000. } forsec level[ 7] { insert naf2 gbar_naf2 = 0.01 insert nap gbar_nap = 0.0001 insert kdr_fs gbar_kdr_fs = 0.01 insert kc_fast gbar_kc_fast = 0.025 insert ka gbar_ka = 0.001 insert km gbar_km = 0.0005 insert k2 gbar_k2 = 0.0005 insert kahp_slower gbar_kahp_slower = 0.0001 insert cal gbar_cal = 0.0002 insert cat gbar_cat = 0.002 insert ar gbar_ar = 2.5E-05 insert cad // *** ca diffusion: beta=1/tau beta_cad = 0.05 // cafor(I) (FORTRAN) converted to phi (NEURON) phi_cad = 520000. } forsec level[ 8] { insert naf2 gbar_naf2 = 0.01 insert nap gbar_nap = 0.0001 insert kdr_fs gbar_kdr_fs = 0.01 insert kc_fast gbar_kc_fast = 0.025 insert ka gbar_ka = 0.001 insert km gbar_km = 0.0005 insert k2 gbar_k2 = 0.0005 insert kahp_slower gbar_kahp_slower = 0.0001 insert cal gbar_cal = 0.0002 insert cat gbar_cat = 0.002 insert ar gbar_ar = 2.5E-05 insert cad // *** ca diffusion: beta=1/tau beta_cad = 0.05 // cafor(I) (FORTRAN) converted to phi (NEURON) phi_cad = 520000. } forsec level[ 9] { insert naf2 gbar_naf2 = 0.01 insert nap gbar_nap = 0.0001 insert kdr_fs gbar_kdr_fs = 0.01 insert kc_fast gbar_kc_fast = 0.025 insert ka gbar_ka = 0.001 insert km gbar_km = 0.0005 insert k2 gbar_k2 = 0.0005 insert kahp_slower gbar_kahp_slower = 0.0001 insert cal gbar_cal = 0.0002 insert cat gbar_cat = 0.002 insert ar gbar_ar = 2.5E-05 insert cad // *** ca diffusion: beta=1/tau beta_cad = 0.05 // cafor(I) (FORTRAN) converted to phi (NEURON) phi_cad = 520000. } forsec all { cm = 1. // assign global specific capac. } // // passive membrane resistance (leak) and axial resistance // forsec Soma_Dendrites { g_pas = 4.E-05 Ra = 200. } forsec Axon { g_pas = 0.001 Ra = 100. } ceiling_cad = 1e6 // nearly unlimited Ca concentration // print "made it to end of initialization from SCORTMAJ_FRB()" } // end of biophys // Compartment Area: Dendritic.spines double area of // dend. membrane, which in Traubs method is equivalent to // only multiplying all dend. max conductances by two // (the area is doubled but the volume is const.) proc double_dend_cond() { spine_area_multiplier = 2 forsec Dendrites { if (ismembrane("nap")) { gbar_nap *= spine_area_multiplier } if (ismembrane("napf")) { gbar_napf *= spine_area_multiplier } if (ismembrane("napf_tcr")) { gbar_napf_tcr *= spine_area_multiplier } if (ismembrane("naf2")) { gbar_naf2 *= spine_area_multiplier } if (ismembrane("naf2_tcr")) { gbar_naf2_tcr *= spine_area_multiplier } if (ismembrane("naf22")) { gbar_naf22 *= spine_area_multiplier } if (ismembrane("kc_fast")) { gbar_kc_fast *= spine_area_multiplier } if (ismembrane("kc_fast_fast")) { gbar_kc_fast_fast *= spine_area_multiplier } if (ismembrane("kahp")) { gbar_kahp *= spine_area_multiplier } if (ismembrane("kahp_slower")) { gbar_kahp_slower *= spine_area_multiplier } if (ismembrane("km")) { gbar_km *= spine_area_multiplier } if (ismembrane("kdr_fs")) { gbar_kdr_fs *= spine_area_multiplier } if (ismembrane("kdr_fs_fs")) { gbar_kdr_fs_fs *= spine_area_multiplier } if (ismembrane("ka")) { gbar_ka *= spine_area_multiplier } if (ismembrane("ka_ib")) { gbar_ka_ib *= spine_area_multiplier } if (ismembrane("k2")) { gbar_k2 *= spine_area_multiplier } if (ismembrane("cal")) { gbar_cal *= spine_area_multiplier } if (ismembrane("cat")) { gbar_cat *= spine_area_multiplier } if (ismembrane("cat_a")) { gbar_cat_a *= spine_area_multiplier } if (ismembrane("ar")) { gbar_ar *= spine_area_multiplier } if (ismembrane("pas")) { g_pas *= spine_area_multiplier } cm = cm * spine_area_multiplier } } // double_dend_cond() // run for cells w/ spines // The below is after doubling of dendritic area to // take into account the effect of spines // These areas were used in the FORTRAN code to // compute the conductances from specific conductances. // I AREA(I) (compartments and their areas) // 1 942.477 // 2 266.406832 // 3 167.551467 // 4 167.551467 // 5 105.299143 // 6 105.299143 // 7 167.551467 // 8 105.299143 // 9 105.299143 // 10 167.551467 // 11 105.299143 // 12 105.299143 // 13 105.299143 // 14 105.299143 // 15 266.406832 // 16 167.551467 // 17 167.551467 // 18 105.299143 // 19 105.299143 // 20 167.551467 // 21 105.299143 // 22 105.299143 // 23 167.551467 // 24 105.299143 // 25 105.299143 // 26 105.299143 // 27 105.299143 // 28 266.406832 // 29 167.551467 // 30 167.551467 // 31 105.299143 // 32 105.299143 // 33 167.551467 // 34 105.299143 // 35 105.299143 // 36 167.551467 // 37 105.299143 // 38 105.299143 // 39 105.299143 // 40 105.299143 // 41 266.406832 // 42 167.551467 // 43 167.551467 // 44 105.299143 // 45 105.299143 // 46 167.551467 // 47 105.299143 // 48 105.299143 // 49 167.551467 // 50 105.299143 // 51 105.299143 // 52 105.299143 // 53 105.299143 // 54 219.9113 // 55 188.4954 // 56 157.0795 // 57 157.0795 // 58 157.0795 // 59 157.0795 proc position() { local i // comp switched to comp[1] since 0 deleted comp[1] for i = 0, n3d()-1 { pt3dchange(i, $1-x+x3d(i), \ $2-y+y3d(i), $3-z+z3d(i),diam3d(i)) } x=$1 y=$2 z=$3 } proc connect2target() { // $o1 targ point process, $o2 returned NetCon comp[presyn_comp] $o2 = new NetCon(&v(1),$o1) $o2.threshold = 0 } objref syn_ proc synapses() { // place for each compartment that has input // statements like //comp[3] syn_=new AlphaSynKinT(1) synlist.append(syn_) //comp[4] syn_=new NMDA(1) synlist.append(syn_) } // is not an artificial cell: func is_art() { return 0 } proc more_adjustments() { forsec all { if (ismembrane("naf2")) {fastNa_shift_naf2=-2.5} // global reversal potentials ek = -100. e_pas = -65. ena = 50. vca = 125. forsec all if (ismembrane("ar")) erev_ar = -40. e_gaba_a = -75. } // more extended initializations // Note: the following currents are not // present in fast spiking and LTS interneurons // Would be slightly more efficient to not include them forsec all { if (ismembrane("nap")) {gbar_nap = 0.0} if (ismembrane("k2")) {gbar_k2 = 0.0} if (ismembrane("km")) {gbar_km = 0.0} if (ismembrane("kahp")) {gbar_kahp = 0.0} if (ismembrane("kahp_slower")) {gbar_kahp_slower = 0.0} if (ismembrane("cat")) {gbar_cat = 0.0} if (ismembrane("ar")) {gbar_ar = 0.0} } } endtemplate deepbask