TITLE Sodium persistent current for RD Traub et al 2003, 2005 COMMENT This persistent sodium current is based on the activation permissive quantity, m, from the transient sodium channel. -TMM modified from an Implementation by Maciej Lazarewicz 2003 (mlazarew@seas.upenn.edu) fastNashift init to 0 and removed from arg modification Tom Morse 3/8/2006 (for Traub et al 2005) ENDCOMMENT INDEPENDENT { t FROM 0 TO 1 WITH 1 (ms) } UNITS { (mV) = (millivolt) (mA) = (milliamp) } NEURON { SUFFIX napf_spinstell : this and the nRT napf differ by -2.5 mV shift in tables USEION na READ ena WRITE ina RANGE gbar, ina,m, df, fastNa_shift, a, b, c, d, minf, mtau } PARAMETER { fastNa_shift = -2.5 (mV) a = 0 (1) b = 0 (1) c = 0 (1) d = 0 (1) gbar = 0.0 (mho/cm2) v (mV) ena (mV) } ASSIGNED { ina (mA/cm2) minf (1) mtau (ms) df (mV) } STATE { m } BREAKPOINT { SOLVE states METHOD cnexp ina = gbar * m * m * m * ( v - ena ) df = v - ena } INITIAL { settables( v ) m = minf m = 0 } DERIVATIVE states { settables( v ) m' = ( minf - m ) / mtau } UNITSOFF PROCEDURE settables(v1(mV)) { TABLE minf, mtau FROM -120 TO 40 WITH 641 minf = 1 / ( 1 + exp( ( - ( v1 + fastNa_shift ) - 38 ) / 10 ) ) if( ( v1 + fastNa_shift ) < -30.0 ) { mtau = 0.025 + 0.14 * exp( ( ( v1 + fastNa_shift ) + 30 ) / 10 ) } else { mtau = 0.02 + a + (0.145+ b) * exp( ( - ( v1 + fastNa_shift +d ) - 30 ) / (10+c) ) } } UNITSON