This demo simulates synaptic bombardment of "in vivo like" conditions in neocortical pyramidal neurons, based on the model detailed in

Destexhe, A. and Pare D. Impact of network activity on the integrative properties of neocortical pyramidal neurons in vivo. J. Neurophysiol. 81: 1531-1547, 1999.
doi: 10.1152/jn.1999.81.4.1531

These model files were contributed by A Destexhe. A PDF copy of this paper is available in

(see this paper for all details)

Compile the mod files with nrnivmodl (linux); for additional platforms (for microsoft windows replace corrgen8.mod with before compiling mod files) and detailed help please consult the following if needed:

Start with a command like:

nrngui mosinit.hoc

Select a simulation to run from the buttons in the GUI

For example selecting "Active precise", and then "Run + calc histogram" should create the following figures