Modeling single neuron LFPs and extracellular potentials with LFPsim (Parasuram et al. 2016)

 Download zip file 
Help downloading and running models
Accession:190140
LFPsim - Simulation scripts to compute Local Field Potentials (LFP) from cable compartmental models of neurons and networks implemented in the NEURON simulation environment.
References:
1 . Parasuram H, Nair B, D'Angelo E, Hines M, Naldi G, Diwakar S (2016) Computational Modeling of Single Neuron Extracellular Electric Potentials and Network Local Field Potentials using LFPsim. Front Comput Neurosci 10:65 [PubMed]
2 . Diwakar S, Medini C, Nair M, Parasuram H, Vijayan A, Nair B (2017) Computational Neuroscience of Timing, Plasticity and Function in Cerebellum Microcircuits (Chapter 12) Computational Neurology and Psychiatry, Springer Series in Bio-/Neuroinformatics, √Črdi P:et al, ed. pp.343
Model Information (Click on a link to find other models with that property)
Model Type: Extracellular;
Brain Region(s)/Organism:
Cell Type(s): Cerebellum interneuron granule GLU cell; Hippocampus CA1 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Extracellular Fields; Methods;
Implementer(s): Parasuram, Harilal [harilalp@am.amrita.edu]; Diwakar, Shyam [shyam at amrita.edu];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal GLU cell; Cerebellum interneuron granule GLU cell;
: lfp.mod

COMMENT
LFPsim - Simulation scripts to compute Local Field Potentials (LFP) from cable compartmental models of neurons and networks implemented in NEURON simulation environment.

LFPsim works reliably on biophysically detailed multi-compartmental neurons with ion channels in some or all compartments.

Last updated 12-March-2016
Developed by : Harilal Parasuram & Shyam Diwakar
Computational Neuroscience & Neurophysiology Lab, School of Biotechnology, Amrita University, India.
Email: harilalp@am.amrita.edu; shyam@amrita.edu
www.amrita.edu/compneuro 
ENDCOMMENT

NEURON {
	SUFFIX lfp
	POINTER transmembrane_current
	RANGE lfp_line,lfp_point,lfp_rc,initial_part_point, initial_part_line, initial_part_rc
	
}


ASSIGNED {

	initial_part_line 
	initial_part_rc
	transmembrane_current 
	lfp_line
	lfp_point
	lfp_rc
	initial_part_point


}

BREAKPOINT { 

	:Point Source Approximation 	
	lfp_point =   transmembrane_current * initial_part_point * 1e-1   : So the calculated signal will be in nV

	:Line Source Approximation
	lfp_line =   transmembrane_current * initial_part_line  * 1e-1  : So the calculated signal will be in nV

	:RC
	lfp_rc =   transmembrane_current * initial_part_rc * 1e-3 : So the calculated signal will be in nV

}



Loading data, please wait...