### Sample Entropy (SampEn) method (Neymotin et al. 2010)

Accession:137995
"... To determine the complexity of the EEG time series, we calculated the sample entropy (SampEn) .... SampEn is the negative natural logarithm of an estimate of the conditional probability that subseries (epochs) of length m-1 that match pointwise within a tolerance r also match at the mth point. ..."
Tool Information (Click on a link to find other Tools with that property)
 Tool Type: Analysis; Statistics; Simulation Environment: NEURON;
 \ sampendemo readme.txt misc.mod sampen.mod vecst.mod mosinit.hoc misc.h
```// \$Id: mosinit.hoc,v 1.4 2011/03/16 19:37:28 samn Exp \$

install_vecst() // make sure utility,misc Vector functions available
install_sampen() // make sure vsampen Vector function available

objref vx,vy,g,rdm,vs,vn
strdef str
g=new Graph()
vx=new Vector()
vx.indgen(0,50*2*PI,0.1)
vy=new Vector()
rdm=new Random()
vs=new Vector()
vn=new Vector()
noise = 0
double sz[4]

//* setwave - sets up waveform in vy
proc setwave () { local i,j,n localobj vr
n=\$1
vy.copy(vx)
vy.apply("sin")
vr=new Vector(vy.size)
rdm.uniform(-n,n)
vr.setrand(rdm)
}

//* plotwave - plots waveform in vy using current noise level
proc plotwave () {
g.erase_all()
setwave(noise)
sprint(str,"noise=%g,SampEn=%g",noise,vy.vsampen())
vy.plot(g,vx)
g.size(&sz)
g.size(0,3*2*PI,sz[2],sz[3])
g.label(0.45,0.94,str)
}

//* plotsvn - calculates/plots SampEn vs noise level
proc plotsvn () { local i
vs.resize(0)
vn.indgen(0,2.5,0.1)
for i=0,vn.size-1 {
setwave(vn.x(i))
vs.append(vy.vsampen())
}
g.erase_all
vs.plot(g,vn,1,4)
vs.mark(g,vn,"O",15,1,1)
g.label(0.77,0.025,"noise level")
g.label(0.,0.9,"SampEn")
}

xpanel("help")
xlabel("NEURON demo of Sample Entropy (SampEn)")
xlabel("plot SampEn vs noise - applies different levels of noise to sin wave and calculates SampEn - plots results")
xlabel("plot waveform with noise level - plots sin wave using specified noise level")
xlabel("noise - specify noise level for plot waveform with noise level button")
xpanel()
}

//* dempan - GUI
proc dempan () {
xpanel("NEURON demo of Sample Entropy (SampEn)")
xbutton("plot SampEn vs noise","plotsvn()")
xbutton("plot waveform with noise level","plotwave()")
xvalue("noise","noise",1)